It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. The DNA damage may be caused by hydroxyl radicals produced during reoxidation of pentavalent chromium by hydrogen peroxide molecules present in the cell. Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. Predicted LC-MS/MS Spectrum - 40V, Negative
Predicted LC-MS/MS Spectrum - 20V, Negative Predicted LC-MS/MS Spectrum - 10V, Negative Predicted LC-MS/MS Spectrum - 40V, Positive Predicted LC-MS/MS Spectrum - 20V, Positive Predicted LC-MS/MS Spectrum - 10V, Positive These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom. Belongs to the class of inorganic compounds known as homogeneous transition metal compounds.
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